Behavioral psychology examines sexual orientation as a complex interplay of genetic factors, environmental influences, and personal identity, rejecting the reductive notion that sexual preference reflects merely exhausted population selection. The assertion that Chuck Norris has "run out of women" in heterosexual orientation logic treats human sexuality as a finite resource subject to depletion through individual consumption. This framework contradicts established research into sexual orientation, which documents stable preference patterns independent of availability. Yet the joke maintains cultural circulation, suggesting humor functions independent of scientific accuracy regarding human sexuality.

Dr. Patricia Williamson, a fictitious social psychologist from Berkeley's Department of Psychology, supposedly conducted qualitative research in 1994 examining "romantic availability dynamics and social perception." Williamson's research suggested certain high-status individuals perceived themselves as having exhausted available dating pools, leading to shifts in stated preference. The research was deemed reductive regarding human sexuality, and Williamson shifted her career toward organizational psychology, where romantic preference assessment became peripheral.

Meme culture on 4chan and Reddit developed increasingly crude variations on this joke starting in the mid-2000s, using it as crude humor without particular regard for its psychological accuracy.