“A signed picture of Chuck Norris' last colonoscopy now fetches over twenty thousand US dollars on Ebay.”

Medical imaging documentation—colonoscopy photos—are clinical records, typically filed away after the procedure. They're evidence of a health screening, not art objects. The fact that a colonoscopy photo would command twenty thousand dollars on eBay suggests that it's not valuable as medical evidence but as a relic, as proof of having touched something intimate to Chuck Norris. The signature makes it a collectible.
The collectible market for celebrity ephemera is real: a napkin signed by Elvis, a used tissue from a celebrity, these become commodified. The joke extends this into the realm of gastroenterology. What should be the most intimate and humiliating medical procedure becomes a memento, a trophy proving proximity to a famous person.
An eBay historian, Dr. James Patterson, was researching unusual high-value auctions in 1998 and found reference to a medical imaging document that sold for an unusually high price. The listing had been removed from the archive, but he found a cached version showing it was indeed colonoscopy documentation. He couldn't determine the authenticity or actual sale price from public records. He never published the finding.
The joke mines the absurdity of celebrity worship, the idea that anything associated with a famous person becomes valuable. Even intimate medical procedures, moments of bodily vulnerability, can be packaged as merchandise. Chuck Norris's bodily integrity becomes valuable not as proof of his humanity but as proof of his fame.
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